5-Bromo-2-fluoro-3-nitro-benzoic acid methyl ester
Methyl 5-bromo-2-fluoro-3-nitrobenzoate
CAS: 1154278-17-7
Molecular Formula: C8H5BrFNO4
5-Bromo-2-fluoro-3-nitro-benzoic acid methyl ester - Names and Identifiers
5-Bromo-2-fluoro-3-nitro-benzoic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C8H5BrFNO4 |
| Molar Mass | 278.03 |
| Density | 1.742±0.06 g/cm3(Predicted) |
| Boling Point | 345.4±42.0 °C(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | IRRITANT |
| MDL | MFCD12172992 |
5-Bromo-2-fluoro-3-nitro-benzoic acid methyl ester - Introduction
Methyl is an organic compound with the chemical formula C8H5BrFNO4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 42-44 degrees Celsius
-Boiling point: 300 degrees Celsius
-Relative density: 1.69
-Stability: The compound is unstable under light and should be avoided from exposure to sunlight.
Use:
- Methyl is often used as an intermediate in organic synthesis, especially for the preparation of other organic compounds.
-It can also be used to prepare drugs, pesticides, etc.
Preparation Method:
Methyl can be prepared by the following steps:
1. First, p-nitrobenzene boronic acid reacts with methyl iodide under appropriate reaction conditions to obtain methyl p-nitrobenzene.
2. Then, under alkaline conditions, methyl p-nitrobenzene reacts with tribromomethane to generate methyl 5-bromo-2-methyl-3-nitrobenzoate.
3. Finally, in the presence of a fluorinating reagent, methyl 5-bromo-2-methyl-3-nitrobenzoate is subjected to a fluorination reaction to obtain the target product Metyl.
Safety Information:
-The compound is used and stored in accordance with general laboratory safety procedures.
-It may be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as safety glasses, gloves and respiratory protection when handling.
-Avoid inhaling its powder or smoke, and ensure that the operating area is well ventilated.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 42-44 degrees Celsius
-Boiling point: 300 degrees Celsius
-Relative density: 1.69
-Stability: The compound is unstable under light and should be avoided from exposure to sunlight.
Use:
- Methyl is often used as an intermediate in organic synthesis, especially for the preparation of other organic compounds.
-It can also be used to prepare drugs, pesticides, etc.
Preparation Method:
Methyl can be prepared by the following steps:
1. First, p-nitrobenzene boronic acid reacts with methyl iodide under appropriate reaction conditions to obtain methyl p-nitrobenzene.
2. Then, under alkaline conditions, methyl p-nitrobenzene reacts with tribromomethane to generate methyl 5-bromo-2-methyl-3-nitrobenzoate.
3. Finally, in the presence of a fluorinating reagent, methyl 5-bromo-2-methyl-3-nitrobenzoate is subjected to a fluorination reaction to obtain the target product Metyl.
Safety Information:
-The compound is used and stored in accordance with general laboratory safety procedures.
-It may be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as safety glasses, gloves and respiratory protection when handling.
-Avoid inhaling its powder or smoke, and ensure that the operating area is well ventilated.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54
